Simulate spatially-aware mixtures in an `scbench` object

Usage

mixtures_spatial(
  scbench,
  n_samples = 20,
  n_spots = 2048,
  n_zones = 4,
  majority_var = 0.15,
  min_majority_prop = 0.3,
  seed = 1,
  ncores = 8,
  ...
)

Arguments

scbench: an `scbench` object
n_samples: an integer representing the number of samples to simulate
n_spots: an integer representing the number of spots to simulate within each sample
n_zones: the number of different zones to generate per slide with different transcriptomic profiles
majority_var: variation parameter related to how much the "majority" population proportion varies within a zone (range: 0 - 0.3)
min_majority_prop: minimum proportion of the "majority" population in a zone
seed: an integer representing a "seed", for reproducibility of mixtures.
...: arguments passed to `fields::circulantEmbeddingSetup` related to the simulation of the Random Gaussian Field

Value

an object of class `scbench`