Compute reference signature matrix from `screference` object using method implemented in DWLS package for methods `dwls`, `svr` and `ols`

Compute reference signature matrix from `screference` object using method implemented in DWLS package for methods `dwls`, `svr` and `ols`

Usage

dwls_scref(scref, cache_path = "dwls", logFC_cutoff = 0.5, pval_cutoff = 0.01)

Arguments

scref

an object of `screference`

cache_path

path to cache results

logFC_cutoff

a float, cutoff for log fold-change from differential expression analysis between populations for selection of markers

pval_cutoff

a float, p-value cutoff from differential expression analysis for selection of markers

Value

a signature matrix